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Non-Canonical Role of IKKα in the Regulation of STAT1 Phosphorylation in Antiviral Signaling

Non-self RNA is recognized by retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), inducing type I interferons (IFNs). Type I IFN promotes the expression of IFN-stimulated genes (ISGs), which requires the activation of signal transducer and activator of transcription-1 (STAT1). We previousl...

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Detalles Bibliográficos
Autores principales: Xing, Fei, Matsumiya, Tomoh, Shiba, Yuko, Hayakari, Ryo, Yoshida, Hidemi, Imaizumi, Tadaatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167405/
https://www.ncbi.nlm.nih.gov/pubmed/27992555
http://dx.doi.org/10.1371/journal.pone.0168696