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Usefulness of DNA Methylation Levels in COASY and SPINT1 Gene Promoter Regions as Biomarkers in Diagnosis of Alzheimer’s Disease and Amnestic Mild Cognitive Impairment

In order to conduct early therapeutic interventions for Alzheimer’s disease (AD), convenient, early diagnosis markers are required. We previously reported that changes in DNA methylation levels were associated with amnestic mild cognitive impairment (aMCI) and AD. As the results suggested changes in...

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Detalles Bibliográficos
Autores principales: Kobayashi, Nobuyuki, Shinagawa, Shunichiro, Nagata, Tomoyuki, Shimada, Kazuya, Shibata, Nobuto, Ohnuma, Tohru, Kasanuki, Koji, Arai, Heii, Yamada, Hisashi, Nakayama, Kazuhiko, Kondo, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167410/
https://www.ncbi.nlm.nih.gov/pubmed/27992572
http://dx.doi.org/10.1371/journal.pone.0168816