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Usefulness of DNA Methylation Levels in COASY and SPINT1 Gene Promoter Regions as Biomarkers in Diagnosis of Alzheimer’s Disease and Amnestic Mild Cognitive Impairment
In order to conduct early therapeutic interventions for Alzheimer’s disease (AD), convenient, early diagnosis markers are required. We previously reported that changes in DNA methylation levels were associated with amnestic mild cognitive impairment (aMCI) and AD. As the results suggested changes in...
Autores principales: | Kobayashi, Nobuyuki, Shinagawa, Shunichiro, Nagata, Tomoyuki, Shimada, Kazuya, Shibata, Nobuto, Ohnuma, Tohru, Kasanuki, Koji, Arai, Heii, Yamada, Hisashi, Nakayama, Kazuhiko, Kondo, Kazuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167410/ https://www.ncbi.nlm.nih.gov/pubmed/27992572 http://dx.doi.org/10.1371/journal.pone.0168816 |
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