Preparation and physicochemical characterization of spray-dried and jet-milled microparticles containing bosentan hydrate for dry powder inhalation aerosols

The objectives of this study were to prepare bosentan hydrate (BST) microparticles as dry powder inhalations (DPIs) via spray drying and jet milling under various parameters, to comprehensively characterize the physicochemical properties of the BST hydrate microparticles, and to evaluate the aerosol...

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Detalles Bibliográficos
Autores principales: Lee, Hyo-Jung, Kang, Ji-Hyun, Lee, Hong-Goo, Kim, Dong-Wook, Rhee, Yun-Seok, Kim, Ju-Young, Park, Eun-Seok, Park, Chun-Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167478/
https://www.ncbi.nlm.nih.gov/pubmed/28008226
http://dx.doi.org/10.2147/DDDT.S120356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167478/
https://www.ncbi.nlm.nih.gov/pubmed/28008226
http://dx.doi.org/10.2147/DDDT.S120356

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