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A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection

Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) was first identified in 2012, and it continues to threaten human health worldwide. No MERS vaccines are licensed for human use, reinforcing the urgency to develop safe and efficacious vaccines to prevent MERS. MERS-CoV spike protein form...

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Detalles Bibliográficos
Autores principales: Tai, Wanbo, Zhao, Guangyu, Sun, Shihun, Guo, Yan, Wang, Yufei, Tao, Xinrong, Tseng, Chien-Te K., Li, Fang, Jiang, Shibo, Du, Lanying, Zhou, Yusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167628/
https://www.ncbi.nlm.nih.gov/pubmed/27750111
http://dx.doi.org/10.1016/j.virol.2016.10.005