Challenges in Drug Discovery for Neurofibromatosis Type 1-Associated Low-Grade Glioma

Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder that results from germline mutations of the NF1 gene, creating a predisposition to low-grade gliomas (LGGs; pilocytic astrocytoma) in young children. Insufficient data and resources represent major challenges to identifying the best po...

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Detalles Bibliográficos
Autores principales: Ricker, Cora A., Pan, Yuan, Gutmann, David H., Keller, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167692/
https://www.ncbi.nlm.nih.gov/pubmed/28066715
http://dx.doi.org/10.3389/fonc.2016.00259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167692/
https://www.ncbi.nlm.nih.gov/pubmed/28066715
http://dx.doi.org/10.3389/fonc.2016.00259

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