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Incorporation of GM-CSF or CD40L Enhances the Immunogenicity of Hantaan Virus-Like Particles
A safe and effective Hantaan virus (HTNV) vaccine is highly desirable because HTNV causes an acute and often fatal disease (hemorrhagic fever with renal syndrome, HFRS). Since the immunity of the inactivated vaccine is weak and the safety is poor, HTNV virus-like particles (VLPs) offer an attractive...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167722/ https://www.ncbi.nlm.nih.gov/pubmed/28066721 http://dx.doi.org/10.3389/fcimb.2016.00185 |