Early Cognitive/Social Deficits and Late Motor Phenotype in Conditional Wild-Type TDP-43 Transgenic Mice

Frontotemporal Dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two neurodegenerative diseases associated to mislocalization and aggregation of TAR DNA-binding protein 43 (TDP-43). To investigate in depth the behavioral phenotype associated with this proteinopathy, we used as a model trans...

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Detalles Bibliográficos
Autores principales: Alfieri, Julio A., Silva, Pablo R., Igaz, Lionel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167738/
https://www.ncbi.nlm.nih.gov/pubmed/28066234
http://dx.doi.org/10.3389/fnagi.2016.00310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167738/
https://www.ncbi.nlm.nih.gov/pubmed/28066234
http://dx.doi.org/10.3389/fnagi.2016.00310

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