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Early Cognitive/Social Deficits and Late Motor Phenotype in Conditional Wild-Type TDP-43 Transgenic Mice

Frontotemporal Dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two neurodegenerative diseases associated to mislocalization and aggregation of TAR DNA-binding protein 43 (TDP-43). To investigate in depth the behavioral phenotype associated with this proteinopathy, we used as a model trans...

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Detalles Bibliográficos
Autores principales:	Alfieri, Julio A., Silva, Pablo R., Igaz, Lionel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167738/ https://www.ncbi.nlm.nih.gov/pubmed/28066234 http://dx.doi.org/10.3389/fnagi.2016.00310

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