The aminoguanidine carboxylate BVT.12777 activates ATP-sensitive K(+ )channels in the rat insulinoma cell line, CRI-G1

BACKGROUND: 3-guanidinopropionic acid derivatives reduce body weight in obese, diabetic mice. We have assessed whether one of these analogues, the aminoguanidine carboxylate BVT.12777, opens K(ATP )channels in rat insulinoma cells, by the same mechanism as leptin. RESULTS: BVT.12777 hyperpolarized C...

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Detalles Bibliográficos
Autores principales: Kinsella, Jackie M, Laidlaw, Hilary A, Tang, Teresa, Harvey, Jenni, Sutherland, Calum, Ashford, Michael LJ
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516774/
https://www.ncbi.nlm.nih.gov/pubmed/15329154
http://dx.doi.org/10.1186/1471-2210-4-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516774/
https://www.ncbi.nlm.nih.gov/pubmed/15329154
http://dx.doi.org/10.1186/1471-2210-4-17

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