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SOD1 Lysine 123 Acetylation in the Adult Central Nervous System
Superoxide dismutase 1 (SOD1) knockout (Sod1(−/−)) mice exhibit an accelerated aging phenotype. In humans, SOD1 mutations are linked to familial amyotrophic lateral sclerosis (ALS), and post-translational modification (PTM) of wild-type SOD1 has been associated with sporadic ALS. Reversible acetylat...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167747/ https://www.ncbi.nlm.nih.gov/pubmed/28066183 http://dx.doi.org/10.3389/fncel.2016.00287 |