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SOD1 Lysine 123 Acetylation in the Adult Central Nervous System

Superoxide dismutase 1 (SOD1) knockout (Sod1(−/−)) mice exhibit an accelerated aging phenotype. In humans, SOD1 mutations are linked to familial amyotrophic lateral sclerosis (ALS), and post-translational modification (PTM) of wild-type SOD1 has been associated with sporadic ALS. Reversible acetylat...

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Detalles Bibliográficos
Autores principales: Kaliszewski, Michael, Kennedy, Austin K., Blaes, Shelby L., Shaffer, Robert S., Knott, Andrew B., Song, Wenjun, Hauser, Henry A., Bossy, Blaise, Huang, Ting-Ting, Bossy-Wetzel, Ella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167747/
https://www.ncbi.nlm.nih.gov/pubmed/28066183
http://dx.doi.org/10.3389/fncel.2016.00287