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Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinks

The recruitment of FANCM, a conserved DNA translocase and key component of several DNA repair protein complexes, to replication forks stalled by DNA interstrand crosslinks (ICLs) is a step upstream of the Fanconi anemia (FA) repair and replication traverse pathways of ICLs. However, detection of the...

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Detalles Bibliográficos
Autores principales: Ling, Chen, Huang, Jing, Yan, Zhijiang, Li, Yongjiang, Ohzeki, Mioko, Ishiai, Masamichi, Xu, Dongyi, Takata, Minoru, Seidman, Michael, Wang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167996/
https://www.ncbi.nlm.nih.gov/pubmed/28058110
http://dx.doi.org/10.1038/celldisc.2016.47