Doxazosin Stimulates Galectin-3 Expression and Collagen Synthesis in HL-1 Cardiomyocytes Independent of Protein Kinase C Pathway

Doxazosin, a drug commonly prescribed for hypertension and prostate disease, increases heart failure risk. However, the underlying mechanism remains unclear. Galectin-3 is an important mediator that plays a pathogenic role in cardiac hypertrophy and heart failure. In the present study, we investigat...

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Detalles Bibliográficos
Autores principales: Qian, Xiaoqian, Li, Mingyang, Wagner, Mary B., Chen, Guangping, Song, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168465/
https://www.ncbi.nlm.nih.gov/pubmed/28066244
http://dx.doi.org/10.3389/fphar.2016.00495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168465/
https://www.ncbi.nlm.nih.gov/pubmed/28066244
http://dx.doi.org/10.3389/fphar.2016.00495

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