Cargando…

Doxazosin Stimulates Galectin-3 Expression and Collagen Synthesis in HL-1 Cardiomyocytes Independent of Protein Kinase C Pathway

Doxazosin, a drug commonly prescribed for hypertension and prostate disease, increases heart failure risk. However, the underlying mechanism remains unclear. Galectin-3 is an important mediator that plays a pathogenic role in cardiac hypertrophy and heart failure. In the present study, we investigat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qian, Xiaoqian, Li, Mingyang, Wagner, Mary B., Chen, Guangping, Song, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168465/ https://www.ncbi.nlm.nih.gov/pubmed/28066244 http://dx.doi.org/10.3389/fphar.2016.00495

Ejemplares similares

Comments on ALLHAT and doxazosin
por: Krakoff, Lawrence R
Publicado: (2001)

Elucidating a Complicated Enantioselective Metabolic Profile: A Study From Rats to Humans Using Optically Pure Doxazosin
por: Kong, Dezhi, et al.
Publicado: (2022)

Prophylactic doxazosin reduces urinary retention and promotes recovery after total joint arthroplasty: A randomized controlled trial
por: Ding, Zichuan, et al.
Publicado: (2023)

Histone deacetylase inhibitors modulate K(ATP) subunit transcription in HL-1 cardiomyocytes through effects on cholesterol homeostasis
por: Fatima, Naheed, et al.
Publicado: (2015)

Determination of Doxazosin Mesylate in Tablets by RP-HPLC
por: Dhanya, B., et al.
Publicado: (2011)

Doxazosin in the treatment of benign prostatic hypertrophy: an update
por: Wilt, Timothy J, et al.
Publicado: (2006)

Leptin regulates MMP-2, TIMP-1 and collagen synthesis via p38 MAPK in HL-1 murine cardiomyocytes
por: Schram, Kristin, et al.
Publicado: (2010)

Unexpected bradycardia after a first dose of doxazosin
por: Pigot, James Edward, et al.
Publicado: (2022)

Galectins in the Pathogenesis of Common Retinal Disease
por: Caridi, Bruna, et al.
Publicado: (2021)

Circulating Galectin-1 and Galectin-3 in Sera From Patients With Systemic Sclerosis: Associations With Clinical Features and Treatment
por: Sundblad, Victoria, et al.
Publicado: (2021)

Treating nightmares in PTSD with doxazosin: a report of three cases
por: Calegaro, Vitor Crestani, et al.
Publicado: (2019)

The Effects of Verapamil, Hydralazine, and Doxazosin on Renin, Aldosterone, and the Ratio Thereof
por: Veldhuizen, Gregory P., et al.
Publicado: (2021)

Liquiritin Attenuates Lipopolysaccharides-Induced Cardiomyocyte Injury via an AMP-Activated Protein Kinase-Dependent Signaling Pathway
por: Mou, Shan-Qi, et al.
Publicado: (2021)

Water-Soluble Tomato Extract Fruitflow Alters the Phosphoproteomic Profile of Collagen-Stimulated Platelets
por: Zhang, Shenghao, et al.
Publicado: (2021)

Eosinophil-expressed galectin-3 regulates cell trafficking and migration
por: Ge, Xiao Na, et al.
Publicado: (2013)

A Pro-resolving Role for Galectin-1 in Acute Inflammation
por: Law, Hannah L., et al.
Publicado: (2020)

Determination of Alkyl Methanesulfonates in Doxazosin Mesylate by Gas Chromatography-mass Spectrometer
por: Sitaram, C., et al.
Publicado: (2011)

The α1 Antagonist Doxazosin Alters the Behavioral Effects of Cocaine in Rats
por: Haile, Colin N., et al.
Publicado: (2012)

Doxazosin for the treatment of nightmare disorder: A diary-based case study
por: Pallesen, Ståle, et al.
Publicado: (2020)

SAT-211 Is Doxazosin the Right Choice for Preoperative Management of Pheochromocytoma in Pregnancy?
por: Bustos, Mario, et al.
Publicado: (2020)

Cost-Effectiveness of Tamsulosin, Doxazosin, and Terazosin in the Treatment of Benign Prostatic Hyperplasia
por: Ohsfeldt, Robert L., et al.
Publicado: (2004)

Pharmacological Protein Kinase C Modulators Reveal a Pro-hypertrophic Role for Novel Protein Kinase C Isoforms in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Pohjolainen, Lotta, et al.
Publicado: (2021)

The safety and efficacy of doxazosin in medical expulsion therapy for distal ureteric calculi: A meta-analysis
por: Yu, Baozhong, et al.
Publicado: (2021)

Galectin-1 Facilitates Macrophage Reprogramming and Resolution of Inflammation Through IFN-β
por: Yaseen, Hiba, et al.
Publicado: (2020)

Galectin-3, Possible Role in Pathogenesis of Periodontal Diseases and Potential Therapeutic Target
por: Velickovic, Milica, et al.
Publicado: (2021)

Reappraisal of Antihypertensive Medicine Doxazosin and Carvedilol as a Potential Therapeutic for Hepatic Fibrosis
por: Paik, Yong-Han
Publicado: (2016)

Doxazosin treatment of phaeochromocytoma during pregnancy: placental transfer and disposition in breast milk
por: Versmissen, Jorie, et al.
Publicado: (2016)

Doxazosin and Carvedilol Treatment Improves Hepatic Regeneration in a Hamster Model of Cirrhosis
por: Serna-Salas, Sandra Alejandra, et al.
Publicado: (2018)

Berberine Ameliorates High Glucose-Induced Cardiomyocyte Injury via AMPK Signaling Activation to Stimulate Mitochondrial Biogenesis and Restore Autophagic Flux
por: Hang, Weijian, et al.
Publicado: (2018)

Adenosine Kinase on Deoxyribonucleic Acid Methylation: Adenosine Receptor-Independent Pathway in Cancer Therapy
por: Luo, Hao-Yun, et al.
Publicado: (2022)

Impact of mitochondria on nitrite metabolism in HL-1 cardiomyocytes
por: Dungel, Peter, et al.
Publicado: (2013)

Phosphatidylinositol 3-Kinase/AKT Pathway Inhibition by Doxazosin Promotes Glioblastoma Cells Death, Upregulation of p53 and Triggers Low Neurotoxicity
por: Gaelzer, Mariana Maier, et al.
Publicado: (2016)

Selective Myeloid Depletion of Galectin-3 Offers Protection Against Acute and Chronic Lung Injury
por: Humphries, Duncan C., et al.
Publicado: (2021)

Microtubule stabilization promotes the synthesis of type 2 collagen in nucleus pulposus cell by activating hippo-yap pathway
por: Zhang, Xin, et al.
Publicado: (2023)

Corrigendum: Adenosine kinase on deoxyribonucleic acid methylation: Adenosine receptor-independent pathway in cancer therapy
por: Luo, Hao-Yun, et al.
Publicado: (2023)

Benefits and side effects of blood pressure lowering treatment: what was wrong with doxazosin in the ALLHAT?
por: Gavras, Irene, et al.
Publicado: (2001)

A case of doxazosin-induced acute coronary syndrome in a patient with myocardial bridging
por: Cerit, Levent, et al.
Publicado: (2016)

The use of doxazosin before adrenalectomy for pheochromocytoma: is the duration related to intraoperative hemodynamics and postoperative complications?
por: Kong, Hao, et al.
Publicado: (2020)

Suppression of TNBC metastasis by doxazosin, a novel dual inhibitor of c-MET/EGFR
por: Kim, Seongjae, et al.
Publicado: (2023)

Imaging alterations of cardiomyocyte cAMP microdomains in disease
por: Froese, Alexander, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_s050cg30bf358d612m592jkov9