Multicentre randomised placebo-controlled trial of oral anticoagulation with apixaban in systemic sclerosis-related pulmonary arterial hypertension: the SPHInX study protocol

INTRODUCTION: Systemic sclerosis (SSc) is a severe and costly multiorgan autoimmune connective tissue disease characterised by vasculopathy and fibrosis. One of the major causes of SSc-related death is pulmonary arterial hypertension (PAH), which develops in 12–15% of patients with SSc and accounts...

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Detalles Bibliográficos
Autores principales: Calderone, Alicia, Stevens, Wendy, Prior, David, Nandurkar, Harshal, Gabbay, Eli, Proudman, Susanna M, Williams, Trevor, Celermajer, David, Sahhar, Joanne, Wong, Peter K K, Thakkar, Vivek, Dwyer, Nathan, Wrobel, Jeremy, Chin, Weng, Liew, Danny, Staples, Margaret, Buchbinder, Rachelle, Nikpour, Mandana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Rheumatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168661/
https://www.ncbi.nlm.nih.gov/pubmed/27932335
http://dx.doi.org/10.1136/bmjopen-2016-011028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168661/
https://www.ncbi.nlm.nih.gov/pubmed/27932335
http://dx.doi.org/10.1136/bmjopen-2016-011028

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