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DNA Hypomethylation in Intragenic and Intergenic Enhancer Chromatin of Muscle-Specific Genes Usually Correlates with their Expression

Tissue-specific enhancers are critical for gene regulation. In this study, we help elucidate the contribution of muscle-associated differential DNA methylation to the enhancer activity of highly muscle-specific genes. By bioinformatic analysis of 44 muscle-associated genes, we show that preferential...

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Detalles Bibliográficos
Autores principales: Ehrlich, Kenneth C., Paterson, Heather L., Lacey, Michelle, Ehrlich, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168824/
https://www.ncbi.nlm.nih.gov/pubmed/28018137