A New VISTA on combination therapy for negative checkpoint regulator blockade

Negative checkpoint regulators function to restrain T cell responses to maintain tolerance and limit immunopathology. However, in the setting of malignancy, these pathways work in concert to promote immune-mediate escape leading to the development of a clinically overt cancer. In the recent years, c...

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Detalles Bibliográficos
Autores principales: Deng, Jie, Le Mercier, Isabelle, Kuta, Anna, Noelle, Randolph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168856/
https://www.ncbi.nlm.nih.gov/pubmed/28031817
http://dx.doi.org/10.1186/s40425-016-0190-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168856/
https://www.ncbi.nlm.nih.gov/pubmed/28031817
http://dx.doi.org/10.1186/s40425-016-0190-5

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