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A New VISTA on combination therapy for negative checkpoint regulator blockade
Negative checkpoint regulators function to restrain T cell responses to maintain tolerance and limit immunopathology. However, in the setting of malignancy, these pathways work in concert to promote immune-mediate escape leading to the development of a clinically overt cancer. In the recent years, c...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168856/ https://www.ncbi.nlm.nih.gov/pubmed/28031817 http://dx.doi.org/10.1186/s40425-016-0190-5 |