PCR mediated recombination impacts the analysis of hepatitis B Virus covalently closed circular DNA

BACKGROUND: The replication of HBV involves the production of covalently closed circular DNA (cccDNA) from the HBV genome through the repair of virion relaxed circular DNA (rcDNA) in the virion. As cccDNA is the transcription template for HBV genomes, it needs to be eliminated from hepatocytes if th...

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Detalles Bibliográficos
Autores principales: Suspène, Rodolphe, Thiers, Valérie, Vartanian, Jean-Pierre, Wain-Hobson, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168874/
https://www.ncbi.nlm.nih.gov/pubmed/27998270
http://dx.doi.org/10.1186/s12977-016-0318-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168874/
https://www.ncbi.nlm.nih.gov/pubmed/27998270
http://dx.doi.org/10.1186/s12977-016-0318-1

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