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A quantitative structure-activity relationship (QSAR) study of some diaryl urea derivatives of B-RAF inhibitors

In the current study, both ligand-based molecular docking and receptor-based quantitative structure activity relationships (QSAR) modeling were performed on 35 diaryl urea derivative inhibitors of (V600E)B-RAF. In this QSAR study, a linear (multiple linear regressions) and a nonlinear (partial least...

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Detalles Bibliográficos
Autores principales: Sadeghian-Rizi, Sedighe, Sakhteman, Amirhossein, Hassanzadeh, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168880/
https://www.ncbi.nlm.nih.gov/pubmed/28003837
http://dx.doi.org/10.4103/1735-5362.194869