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Lovastatin prevents bleomycin-induced DNA damage to HepG2 cells

Lovastatin as a member of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors is used as a lipid-lowering agent. It can also inhibit the formation of hydrogen peroxide and superoxide anion and finally leads to decline in oxidative stress processes. Here, we evaluated whether lovasta...

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Detalles Bibliográficos
Autores principales: Nasiri, Marjan, Etebari, Mahmoud, Jafarian-Dehkordi, Abbas, Moradi, Shahla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168883/
https://www.ncbi.nlm.nih.gov/pubmed/28003840
http://dx.doi.org/10.4103/1735-5362.194876