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Dynein-mediated trafficking negatively regulates LET-23 EGFR signaling

Epidermal growth factor receptor (EGFR) signaling is essential for animal development, and increased signaling underlies many human cancers. Identifying the genes and cellular processes that regulate EGFR signaling in vivo will help to elucidate how this pathway can become inappropriately activated....

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Detalles Bibliográficos
Autores principales: Skorobogata, Olga, Meng, Jassy, Gauthier, Kimberley, Rocheleau, Christian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170559/
https://www.ncbi.nlm.nih.gov/pubmed/27654944
http://dx.doi.org/10.1091/mbc.E15-11-0757