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Regulation of GPCR expression through an interaction with CCT7, a subunit of the CCT/TRiC complex
Mechanisms that prevent aggregation and promote folding of nascent G protein–coupled receptors (GPCRs) remain poorly understood. We identified chaperonin containing TCP-1 subunit eta (CCT7) as an interacting partner of the β-isoform of thromboxane A(2) receptor (TPβ) by yeast two-hybrid screening. C...
Autores principales: | Génier, Samuel, Degrandmaison, Jade, Moreau, Pierrick, Labrecque, Pascale, Hébert, Terence E., Parent, Jean-Luc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170604/ https://www.ncbi.nlm.nih.gov/pubmed/27708139 http://dx.doi.org/10.1091/mbc.E16-04-0224 |
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