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An NXF1 mRNA with a retained intron is expressed in hippocampal and neocortical neurons and is translated into a protein that functions as an Nxf1 cofactor

The Nxf1 protein is a major nuclear export receptor for the transport of mRNA, and it also is essential for export of retroviral mRNAs with retained introns. In the latter case, it binds to RNA elements known as constitutive transport elements (CTEs) and functions in conjunction with a cofactor know...

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Detalles Bibliográficos
Autores principales: Li, Ying, Bor, Yeou-cherng, Fitzgerald, Mark P., Lee, Kevin S., Rekosh, David, Hammarskjold, Marie-Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170612/
https://www.ncbi.nlm.nih.gov/pubmed/27708137
http://dx.doi.org/10.1091/mbc.E16-07-0515