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Nuclear envelope rupture drives genome instability in cancer

The nuclear envelope, composed of two lipid bilayers and numerous accessory proteins, has evolved to house the genetic material of all eukaryotic cells. In so doing, the nuclear envelope provides a physical barrier between chromosomes and the cytoplasm. Once believed to be highly stable, recent stud...

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Detalles Bibliográficos
Autores principales: Lim, Sanghee, Quinton, Ryan J., Ganem, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170854/
https://www.ncbi.nlm.nih.gov/pubmed/27799497
http://dx.doi.org/10.1091/mbc.E16-02-0098