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Elevated mitochondria-coupled NAD(P)H in endoplasmic reticulum of dopamine neurons

Pyridine nucleotides are redox coenzymes that are critical in bioenergetics, metabolism, and neurodegeneration. Here we use brain slice multiphoton microscopy to show that substantia nigra dopamine neurons, which are sensitive to stress in mitochondria and the endoplasmic reticulum (ER), display ele...

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Detalles Bibliográficos
Autores principales: Tucker, Kristal R., Cavolo, Samantha L., Levitan, Edwin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170855/
https://www.ncbi.nlm.nih.gov/pubmed/27582392
http://dx.doi.org/10.1091/mbc.E16-07-0479