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Roles for E-cadherin cell surface regulation in cancer

The loss of E-cadherin expression in association with the epithelial–mesenchymal transition (EMT) occurs frequently during tumor metastasis. However, metastases often retain E-cadherin expression, an EMT is not required for metastasis, and metastases can arise from clusters of tumor cells. We demons...

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Detalles Bibliográficos
Autores principales: Petrova, Yuliya I., Schecterson, Leslayann, Gumbiner, Barry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170857/
https://www.ncbi.nlm.nih.gov/pubmed/27582386
http://dx.doi.org/10.1091/mbc.E16-01-0058