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Spastin, atlastin, and ER relocalization are involved in axon but not dendrite regeneration

Mutations in >50 genes, including spastin and atlastin, lead to hereditary spastic paraplegia (HSP). We previously demonstrated that reduction of spastin leads to a deficit in axon regeneration in a Drosophila model. Axon regeneration was similarly impaired in neurons when HSP proteins atlastin,...

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Detalles Bibliográficos
Autores principales: Rao, Kavitha, Stone, Michelle C., Weiner, Alexis T., Gheres, Kyle W., Zhou, Chaoming, Deitcher, David L., Levitan, Edwin S., Rolls, Melissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170858/
https://www.ncbi.nlm.nih.gov/pubmed/27605706
http://dx.doi.org/10.1091/mbc.E16-05-0287