Amyloid β-peptides interfere with mitochondrial preprotein import competence by a coaggregation process

Aβ peptides play a central role in the etiology of Alzheimer disease (AD) by exerting cellular toxicity correlated with aggregate formation. Experimental evidence has shown intraneuronal accumulation of Aβ peptides and interference with mitochondrial functions. Nevertheless, the relevance of intrace...

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Detalles Bibliográficos
Autores principales: Cenini, Giovanna, Rüb, Cornelia, Bruderek, Michael, Voos, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170859/
https://www.ncbi.nlm.nih.gov/pubmed/27630262
http://dx.doi.org/10.1091/mbc.E16-05-0313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170859/
https://www.ncbi.nlm.nih.gov/pubmed/27630262
http://dx.doi.org/10.1091/mbc.E16-05-0313

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