Cargando…

Amyloid β-peptides interfere with mitochondrial preprotein import competence by a coaggregation process

Aβ peptides play a central role in the etiology of Alzheimer disease (AD) by exerting cellular toxicity correlated with aggregate formation. Experimental evidence has shown intraneuronal accumulation of Aβ peptides and interference with mitochondrial functions. Nevertheless, the relevance of intrace...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cenini, Giovanna, Rüb, Cornelia, Bruderek, Michael, Voos, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170859/ https://www.ncbi.nlm.nih.gov/pubmed/27630262 http://dx.doi.org/10.1091/mbc.E16-05-0313

Ejemplares similares

IMiQ: a novel protein quality control compartment protecting mitochondrial functional integrity
por: Bruderek, Michael, et al.
Publicado: (2018)

AIP is a mitochondrial import mediator that binds to both import receptor Tom20 and preproteins
por: Yano, Masato, et al.
Publicado: (2003)

Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress
por: Jaworek, Witold, et al.
Publicado: (2022)

Mitochondria as Potential Targets in Alzheimer Disease Therapy: An Update
por: Cenini, Giovanna, et al.
Publicado: (2019)

Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences
por: Backes, Sandra, et al.
Publicado: (2018)

Mgr2 regulates mitochondrial preprotein import by associating with channel-forming Tim23 subunit
por: Matta, Srujan Kumar, et al.
Publicado: (2020)

Analysis of the Interactions of Preproteins with the Import Machinery over the Course of Protein Import into Chloroplasts
por: Kouranov, Andrei, et al.
Publicado: (1997)

Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix
Publicado: (1993)

Coaggregation properties of trimeric autotransporter adhesins
por: Khalil, Hawzeen S., et al.
Publicado: (2020)

The journey of preproteins across the chloroplast membrane systems
por: Ballabani, Gent, et al.
Publicado: (2023)

Biogenesis of the preprotein translocase of the outer mitochondrial membrane: protein kinase A phosphorylates the precursor of Tom40 and impairs its import
por: Rao, Sanjana, et al.
Publicado: (2012)

A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins
Publicado: (1993)

Molecular Interpretation of ACTH-β-Endorphin Coaggregation: Relevance to Secretory Granule Biogenesis
por: Ranganathan, Srivastav, et al.
Publicado: (2012)

Effect of metabolosome encapsulation peptides on enzyme activity, coaggregation, incorporation, and bacterial microcompartment formation
por: Juodeikis, Rokas, et al.
Publicado: (2020)

Coaggregation of polyglutamine (polyQ) proteins is mediated by polyQ-tract interactions and impairs cellular proteostasis: Coaggregation of polyQ proteins
por: Hong, Jun-Ye, et al.
Publicado: (2023)

The role of GTP binding and hydrolysis at the atToc159 preprotein receptor during protein import into chloroplasts
por: Wang, Fei, et al.
Publicado: (2008)

Adhesion Forces and Coaggregation between Vaginal Staphylococci and Lactobacilli
por: Younes, Jessica A., et al.
Publicado: (2012)

Familial Coaggregation of Asthma and Type 1 Diabetes in Children
por: Smew, Awad I., et al.
Publicado: (2020)

Protein folding causes an arrest of preprotein translocation into mitochondria in vivo
Publicado: (1991)

Dimeric SecA Couples the Preprotein Translocation in an Asymmetric Manner
por: Tang, Ying, et al.
Publicado: (2011)

Structure of the SecY Complex Unlocked by a Preprotein Mimic
por: Hizlan, Dilem, et al.
Publicado: (2012)

Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways
por: Bellia, F., et al.
Publicado: (2019)

In vitro uptake and processing of prezein and other maize preproteins by maize membranes
Publicado: (1981)

The preprotein translocase YidC controls respiratory metabolism in Mycobacterium tuberculosis
por: Thakur, Preeti, et al.
Publicado: (2016)

Preprotein mature domains contain translocase targeting signals that are essential for secretion
por: Chatzi, Katerina E., et al.
Publicado: (2017)

Two conformations of the Tom20 preprotein receptor in the TOM holo complex
por: Ornelas, Pamela, et al.
Publicado: (2023)

Rtpca: an R package for differential thermal proximity coaggregation analysis
por: Kurzawa, Nils, et al.
Publicado: (2020)

Transcriptomic Responses to Coaggregation between Streptococcus gordonii and Streptococcus oralis
por: Choo, Siew Woh, et al.
Publicado: (2021)

Heptameric Peptide Interferes with Amyloid-β Aggregation by Structural Reorganization of the Toxic Oligomers
por: Bhattacharyya, Rajanya, et al.
Publicado: (2020)

Coaggregation and biofilm growth of Granulicatella spp. with Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans
por: Karched, Maribasappa, et al.
Publicado: (2015)

Coaggregation of Asthma and Type 1 Diabetes in Children: A Narrative Review
por: Sgrazzutti, Laura, et al.
Publicado: (2021)

Oxidative Stress in Neurodegenerative Diseases: From a Mitochondrial Point of View
por: Cenini, Giovanna, et al.
Publicado: (2019)

Oxidative Stress and Mitochondrial Damage in Neurodegenerative Diseases: From Molecular Mechanisms to Targeted Therapies
por: Cenini, Giovanna, et al.
Publicado: (2020)

The acidic domains of the Toc159 chloroplast preprotein receptor family are intrinsically disordered protein domains
por: Richardson, Lynn GL, et al.
Publicado: (2009)

Interference with Amyloid-β Nucleation by Transient Ligand Interaction
por: Zhang, Tao, et al.
Publicado: (2019)

Porphyromonas gingivalis Outer Membrane Vesicles Mediate Coaggregation and Piggybacking of Treponema denticola and Lachnoanaerobaculum saburreum
por: Grenier, Daniel
Publicado: (2013)

Familial aggregation of Parkinson’s disease and coaggregation with neuropsychiatric diseases: a population-based cohort study
por: Liu, Fu-Chao, et al.
Publicado: (2018)

Familial aggregation and heritability of type 1 diabetes mellitus and coaggregation of chronic diseases in affected families
por: Kuo, Chang-Fu, et al.
Publicado: (2018)

Transcriptional profiling of coaggregation interactions between Streptococcus gordonii and Veillonella parvula by Dual RNA-Seq
por: Mutha, Naresh V. R., et al.
Publicado: (2019)

A Hairpin Motif in the Amyloid-β Peptide Is Important for Formation of Disease-Related Oligomers
por: Khaled, Mohammed, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9iic46hjqi5o4jmegsi24vj535