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Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney

Multicopper ferroxidases (MCFs) play an important role in cellular iron homeostasis. However, the role of MCFs in renal metabolism remains unclear. We used Hephaestin (Heph) and Ceruloplasmin (Cp) single or double (Heph/Cp) knockout (KO) mice to study the roles of MCFs in the kidney. Renal iron leve...

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Detalles Bibliográficos
Autores principales: Jiang, Bo, Liu, Guohao, Zheng, Jiashuo, Chen, Mengxia, Maimaitiming, Zaitunamu, Chen, Min, Liu, Shunli, Jiang, Ruiwei, Fuqua, Brie K., Dunaief, Joshua L., Vulpe, Chris D., Anderson, Gregory J., Wang, Hongwei, Chen, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171654/
https://www.ncbi.nlm.nih.gov/pubmed/27991585
http://dx.doi.org/10.1038/srep39470