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Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney
Multicopper ferroxidases (MCFs) play an important role in cellular iron homeostasis. However, the role of MCFs in renal metabolism remains unclear. We used Hephaestin (Heph) and Ceruloplasmin (Cp) single or double (Heph/Cp) knockout (KO) mice to study the roles of MCFs in the kidney. Renal iron leve...
Autores principales: | Jiang, Bo, Liu, Guohao, Zheng, Jiashuo, Chen, Mengxia, Maimaitiming, Zaitunamu, Chen, Min, Liu, Shunli, Jiang, Ruiwei, Fuqua, Brie K., Dunaief, Joshua L., Vulpe, Chris D., Anderson, Gregory J., Wang, Hongwei, Chen, Huijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171654/ https://www.ncbi.nlm.nih.gov/pubmed/27991585 http://dx.doi.org/10.1038/srep39470 |
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