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Adjunctive treatment of brexpiprazole with fluoxetine shows a rapid antidepressant effect in social defeat stress model: Role of BDNF-TrkB signaling

Addition of low doses of the atypical antipsychotic drug brexpiprazole with selective serotonin reuptake inhibitors (SSRIs) could promote antidepressant effect in patients with major depressive disorder although the precise mechanisms underlying the action of the combination are unknown. Combination...

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Detalles Bibliográficos
Autores principales: Ma, Min, Ren, Qian, Yang, Chun, Zhang, Ji-chun, Yao, Wei, Dong, Chao, Ohgi, Yuta, Futamura, Takashi, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171769/
https://www.ncbi.nlm.nih.gov/pubmed/27991542
http://dx.doi.org/10.1038/srep39209