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Ribavirin suppresses bacterial virulence by targeting LysR-type transcriptional regulators

Targeting bacterial virulence mechanisms without compromising bacterial growth is a promising strategy to prevent drug resistance. LysR-type transcriptional regulators (LTTRs) possess structural conservation across bacterial species and regulate virulence in numerous pathogens, making them attractiv...

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Detalles Bibliográficos
Autores principales: Mandal, Rahul Shubhra, Ta, Atri, Sinha, Ritam, Theeya, Nagaraja, Ghosh, Anirban, Tasneem, Mohsina, Bhunia, Anirban, Koley, Hemanta, Das, Santasabuj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171790/
https://www.ncbi.nlm.nih.gov/pubmed/27991578
http://dx.doi.org/10.1038/srep39454