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Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone

Communication between osteoblasts and endothelial cells (ECs) is essential for bone turnover, but the molecular mechanisms of such communication are not well defined. Here we identify Cxcl9 as an angiostatic factor secreted by osteoblasts in the bone marrow microenvironment. We show that Cxcl9 produ...

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Detalles Bibliográficos
Autores principales: Huang, Bin, Wang, Wenhao, Li, Qingchu, Wang, Zhenyu, Yan, Bo, Zhang, Zhongmin, Wang, Liang, Huang, Minjun, Jia, Chunhong, Lu, Jiansen, Liu, Sichi, Chen, Hongdong, Li, Mangmang, Cai, Daozhang, Jiang, Yu, Jin, Dadi, Bai, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171795/
https://www.ncbi.nlm.nih.gov/pubmed/27966526
http://dx.doi.org/10.1038/ncomms13885