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Biliary Phospholipids Sustain Enterocyte Proliferation and Intestinal Tumor Progression via Nuclear Receptor Lrh1 in mice

The proliferative-crypt compartment of the intestinal epithelium is enriched in phospholipids and accumulation of phospholipids has been described in colorectal tumors. Here we hypothesize that biliary phospholipid flow could directly contribute to the proliferative power of normal and dysplastic en...

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Detalles Bibliográficos
Autores principales: Petruzzelli, Michele, Piccinin, Elena, Pinto, Claudio, Peres, Claudia, Bellafante, Elena, Moschetta, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171812/
https://www.ncbi.nlm.nih.gov/pubmed/27995969
http://dx.doi.org/10.1038/srep39278