Cargando…
Biliary Phospholipids Sustain Enterocyte Proliferation and Intestinal Tumor Progression via Nuclear Receptor Lrh1 in mice
The proliferative-crypt compartment of the intestinal epithelium is enriched in phospholipids and accumulation of phospholipids has been described in colorectal tumors. Here we hypothesize that biliary phospholipid flow could directly contribute to the proliferative power of normal and dysplastic en...
Autores principales: | Petruzzelli, Michele, Piccinin, Elena, Pinto, Claudio, Peres, Claudia, Bellafante, Elena, Moschetta, Antonio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171812/ https://www.ncbi.nlm.nih.gov/pubmed/27995969 http://dx.doi.org/10.1038/srep39278 |
Ejemplares similares
-
Another One Bites the Gut: Nuclear Receptor LRH-1 in Intestinal Regeneration and Cancer
por: Zerlotin, Roberta, et al.
Publicado: (2021) -
Hepatic MicroRNA Expression by PGC-1α and PGC-1β in the Mouse
por: Piccinin, Elena, et al.
Publicado: (2019) -
PGC-1β Induces Susceptibility To Acetaminophen-Driven Acute Liver Failure
por: Piccinin, Elena, et al.
Publicado: (2019) -
Enterocyte superoxide dismutase 2 deletion drives obesity
por: Garcia-Irigoyen, Oihane, et al.
Publicado: (2021) -
The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine
por: Mueller, Matthias, et al.
Publicado: (2006)