tCRISPRi: tunable and reversible, one-step control of gene expression

The ability to control the level of gene expression is a major quest in biology. A widely used approach employs deletion of a nonessential gene of interest (knockout), or multi-step recombineering to move a gene of interest under a repressible promoter (knockdown). However, these genetic methods are...

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Detalles Bibliográficos
Autores principales: Li, Xin-tian, Jun, Yonggun, Erickstad, Michael J., Brown, Steven D., Parks, Adam, Court, Donald L., Jun, Suckjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171832/
https://www.ncbi.nlm.nih.gov/pubmed/27996021
http://dx.doi.org/10.1038/srep39076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171832/
https://www.ncbi.nlm.nih.gov/pubmed/27996021
http://dx.doi.org/10.1038/srep39076

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