A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice

Asthma has multiple features, including airway hyperreactivity, inflammation and remodelling. The TNF superfamily member TNFSF14 (LIGHT), via interactions with the receptor TNFRSF14 (HVEM), can support T(H)2 cell generation and longevity and promote airway remodelling in mouse models of asthma, but...

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Detalles Bibliográficos
Autores principales: Sibilano, Riccardo, Gaudenzio, Nicolas, DeGorter, Marianne K., Reber, Laurent L., Hernandez, Joseph D., Starkl, Philipp M., Zurek, Oliwia W., Tsai, Mindy, Zahner, Sonja, Montgomery, Stephen B., Roers, Axel, Kronenberg, Mitchell, Yu, Mang, Galli, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171877/
https://www.ncbi.nlm.nih.gov/pubmed/27982078
http://dx.doi.org/10.1038/ncomms13696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171877/
https://www.ncbi.nlm.nih.gov/pubmed/27982078
http://dx.doi.org/10.1038/ncomms13696

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