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A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice
Asthma has multiple features, including airway hyperreactivity, inflammation and remodelling. The TNF superfamily member TNFSF14 (LIGHT), via interactions with the receptor TNFRSF14 (HVEM), can support T(H)2 cell generation and longevity and promote airway remodelling in mouse models of asthma, but...
Autores principales: | Sibilano, Riccardo, Gaudenzio, Nicolas, DeGorter, Marianne K., Reber, Laurent L., Hernandez, Joseph D., Starkl, Philipp M., Zurek, Oliwia W., Tsai, Mindy, Zahner, Sonja, Montgomery, Stephen B., Roers, Axel, Kronenberg, Mitchell, Yu, Mang, Galli, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171877/ https://www.ncbi.nlm.nih.gov/pubmed/27982078 http://dx.doi.org/10.1038/ncomms13696 |
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