In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters

Syntaxin1A is organized in nanoclusters that are critical for the docking and priming of secretory vesicles from neurosecretory cells. Whether and how these nanoclusters are affected by neurotransmitter release in nerve terminals from a living organism is unknown. Here we imaged photoconvertible syn...

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Detalles Bibliográficos
Autores principales: Bademosi, Adekunle T., Lauwers, Elsa, Padmanabhan, Pranesh, Odierna, Lorenzo, Chai, Ye Jin, Papadopulos, Andreas, Goodhill, Geoffrey J., Verstreken, Patrik, van Swinderen, Bruno, Meunier, Frédéric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171881/
https://www.ncbi.nlm.nih.gov/pubmed/28045048
http://dx.doi.org/10.1038/ncomms13660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171881/
https://www.ncbi.nlm.nih.gov/pubmed/28045048
http://dx.doi.org/10.1038/ncomms13660

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