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Improvement of gamete quality by stimulating and feeding the endogenous antioxidant system: mechanisms, clinical results, insights on gene-environment interactions and the role of diet

Oxidative damage triggers extensive repair in gametes and thereafter in the zygote but it results in clinically relevant damage when affecting the maturation of the gametes chromatin, i.e. padlocking and epigenetic marking. It associates with defective DNA methylation and/or with oxidation of the me...

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Detalles Bibliográficos
Autores principales: Dattilo, Maurizio, Giuseppe, D’Amato, Ettore, Caroppo, Ménézo, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171888/
https://www.ncbi.nlm.nih.gov/pubmed/27423667
http://dx.doi.org/10.1007/s10815-016-0767-4