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Profiling DNA damage response following mitotic perturbations

Genome integrity relies on precise coordination between DNA replication and chromosome segregation. Whereas replication stress attracted much attention, the consequences of mitotic perturbations for genome integrity are less understood. Here, we knockdown 47 validated mitotic regulators to show that...

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Detalles Bibliográficos
Autores principales: S. Pedersen, Ronni, Karemore, Gopal, Gudjonsson, Thorkell, Rask, Maj-Britt, Neumann, Beate, Hériché, Jean-Karim, Pepperkok, Rainer, Ellenberg, Jan, Gerlich, Daniel W., Lukas, Jiri, Lukas, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172227/
https://www.ncbi.nlm.nih.gov/pubmed/27976684
http://dx.doi.org/10.1038/ncomms13887