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Ubiquitylation Directly Induces Fold Destabilization of Proteins

Ubiquitin is a common post-translational modifier and its conjugation is a key signal for proteolysis by the proteasome. Because the molecular mass of ubiquitin is larger than that of other modifiers such as phosphate, acetyl, or methyl groups, ubiquitylation not only influences biochemical signalin...

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Detalles Bibliográficos
Autores principales: Morimoto, Daichi, Walinda, Erik, Fukada, Harumi, Sugase, Kenji, Shirakawa, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172356/
https://www.ncbi.nlm.nih.gov/pubmed/27991582
http://dx.doi.org/10.1038/srep39453