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Circulating Estradiol Regulates Brain-Derived Estradiol via Actions at GnRH Receptors to Impact Memory in Ovariectomized Rats
Systemic estradiol treatment enhances hippocampus-dependent memory in ovariectomized rats. Although these enhancements are traditionally thought to be due to circulating estradiol, recent data suggest these changes are brought on by hippocampus-derived estradiol, the synthesis of which depends on go...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172373/ https://www.ncbi.nlm.nih.gov/pubmed/28032117 http://dx.doi.org/10.1523/ENEURO.0321-16.2016 |