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Circulating Estradiol Regulates Brain-Derived Estradiol via Actions at GnRH Receptors to Impact Memory in Ovariectomized Rats

Systemic estradiol treatment enhances hippocampus-dependent memory in ovariectomized rats. Although these enhancements are traditionally thought to be due to circulating estradiol, recent data suggest these changes are brought on by hippocampus-derived estradiol, the synthesis of which depends on go...

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Detalles Bibliográficos
Autores principales: Nelson, Britta S., Black, Katelyn L., Daniel, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172373/
https://www.ncbi.nlm.nih.gov/pubmed/28032117
http://dx.doi.org/10.1523/ENEURO.0321-16.2016