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The PI3K-AKT-mTOR pathway activates recovery from general anesthesia

We investigated roles of PI3K-AKT-mTOR pathway in recovery from general anesthesia. Sprague-Dawley rats divided into five groups: saline+artificial cerebrospinal fluid (ACSF; Group A), ketamine+ACSF (Group B), ketamine+IGF-1 (Group C), ketamine+PI3K inhibitor (Group D), and PI3K/Akt agonists (Group...

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Detalles Bibliográficos
Autores principales: Zhang, Yun-Hui, Zhang, Jin, Song, Jian-Nan, Xu, Xue, Cai, Jin-Song, Zhou, Yang, Gao, Jin-Gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173033/
https://www.ncbi.nlm.nih.gov/pubmed/27340771
http://dx.doi.org/10.18632/oncotarget.10172