Interferon regulatory factor 4 attenuates Notch signaling to suppress the development of chronic lymphocytic leukemia

Molecular pathogenesis of Chronic Lymphocytic Leukemia (CLL) is not fully elucidated. Genome wide association studies have linked Interferon Regulatory Factor 4 (IRF4) to the development of CLL. We recently established a causal relationship between low levels of IRF4 and development of CLL. However,...

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Detalles Bibliográficos
Autores principales: Shukla, Vipul, Shukla, Ashima, Joshi, Shantaram S., Lu, Runqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173044/
https://www.ncbi.nlm.nih.gov/pubmed/27232759
http://dx.doi.org/10.18632/oncotarget.9596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173044/
https://www.ncbi.nlm.nih.gov/pubmed/27232759
http://dx.doi.org/10.18632/oncotarget.9596

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