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Interferon regulatory factor 4 attenuates Notch signaling to suppress the development of chronic lymphocytic leukemia
Molecular pathogenesis of Chronic Lymphocytic Leukemia (CLL) is not fully elucidated. Genome wide association studies have linked Interferon Regulatory Factor 4 (IRF4) to the development of CLL. We recently established a causal relationship between low levels of IRF4 and development of CLL. However,...
Autores principales: | Shukla, Vipul, Shukla, Ashima, Joshi, Shantaram S., Lu, Runqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173044/ https://www.ncbi.nlm.nih.gov/pubmed/27232759 http://dx.doi.org/10.18632/oncotarget.9596 |
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