NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma

Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults. The current standard of care includes surgery followed by radiotherapy (RT) and chemotherapy with temozolomide (TMZ). Treatment often fails due to the radiation resistance and intrinsic or acquired TMZ resistance of a...

Descripción completa

Detalles Bibliográficos
Autores principales: Yahyanejad, Sanaz, King, Henry, Iglesias, Venus Sosa, Granton, Patrick V., Barbeau, Lydie M.O., van Hoof, Stefan J., Groot, Arjan J., Habets, Roger, Prickaerts, Jos, Chalmers, Anthony J., Eekers, Daniëlle B.P., Theys, Jan, Short, Susan C., Verhaegen, Frank, Vooijs, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173056/
https://www.ncbi.nlm.nih.gov/pubmed/27183910
http://dx.doi.org/10.18632/oncotarget.9275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173056/
https://www.ncbi.nlm.nih.gov/pubmed/27183910
http://dx.doi.org/10.18632/oncotarget.9275

Ejemplares similares